The Big Bang Theory follows the story of a group of scientists and a waitress who aspires to be an actress. This waitress is beautiful and blonde, making the scientist squad believe that she is, well, dumb.
However, episode after episode, Penny has proved that she is actually a very smart and witty girl who has witty retorts for everything. True that she doesn't possess all the scientific knowledge like her neighbours do but her comebacks sure make her the most interesting person in the squad.
Here's a compilation of comebacks by Penny that prove that she clearly outwitted the group of scientists:
The girl sure knows how to deliver a #burn!
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